I'm pretty new to this forum, but I have been struggling with the same question for quite a while.
At this point, unless I have a reason not to obey those set over me, I do what they ask. Most of the time I find they do not ask me to do anything wrong or call me away from what God is calling me to do. Most of the time they are just seem plain inconvenient. There are plenty of hypothetical situations that I can bring up as reasons to not submit, but mostly it's about my pride or laziness.
I have been trying to move not only into submission, but into honoring others by doing things they ask without complaining, promptly, well, and with a little extra. I want to teach this to my children, too, so the best way is to model it.
The joy of submission is that I have found myself working with God more in many situations I would not have if I had avoided submitting. I also have found less time to sin. . . idle hands are the Devil's workshop. I see my obedience to these leaders as obedience to God, since he has placed them over me.
I still have a long way to go. It is hard to be faithful when their eyes are not on me or when I find their requests meaningless or just plain silly. The practice has beat down my pride quite a bit, however, and made made me more available for God's work wherever he would have me.